46. ӣѡԻøҩ
47. ̩ɺǻ̩ɣͪѡԻøҩиҩøյãɼйӦжҪƷʪԺʪԹؽסƼʹ磬Ҳڼ˿没Ѫ没ķȡӦθӦˮӦҩãյҩøǿ߰ĴлͨѪϲλǿ㶹ڷѪҩڷѪҩӢɺƤʼصá
48. ǿPGϳøҩĿȺʹáڼԷʪԹؽסʹԹؽ֢ʹԡ֧ܲиá
49. ѡյͻøҩ
50. ʹҩжӡ̩ɡҡͪҡ˫ȷᡢ
51. ȫҩ顢顢ѡ顢ǵȰͪԴ
52. ʧҩû1.2.ıĤӦԼԶ۷3.ıERPЧӦڣͶλʱ̣APD۷IAб֡ŵIBɡᡢֶICжᡣIIIаIVеضյض
53. ᶡļϸĤ֬ϣĤơӵͨԣΪĤȶɽԣӳERPϦͿáٴԺԹĶٶЧ˥ӦػơӦҪθӦƷӦѪѹѪ˨ĶͣᶡʺӦļضȷҴ͡ǿ߰жѪػ߽á˥ѪѹΡܲȫá
54. ³ʧҩҪĶ/Ƶ粫ӦθӦӦǴ͡Ѫѹ˥á
55. ҪʧɽԣAPDӳERP,ı䲡ٶȡʧЧ
56. ͪڷԻԹ粫עֹԻĶٺԤۺ֢Ķ١ʧЧ˥Ķ͡Ѫѹ߽áͬҩǶᡢͿᡢᡣ
57. ǰԴ
58. ͪʧҩڷĶٺʧӦĶ
59. ҩάףڷտ죬ЧӦԡļϸĤͨCaҪӰͷҽӦϸɣʧĶѡڰйIJѪѹߡҪθȲӦ˥͡ԭݿ˼ѪѹȽá
60. ҩƽ֬ǿڷѸգиáѪƽļϸCaʹѪͣѪѹ½ļͣŹ״״ΣӹļٴڷĽʹɵڸѪѹӦԭݿˡѪѹĹܲá
61. ҩضڷãܸӰ졣ΪҩŹ״ѪܣʹͣʹἰҽԽ͡ڹIJĽʹơἰжȸѪѹҲнϺЧ겡ˡ2ϷҴ͡Ѫѹ˥иá
62. ĹܲȫѪ˥ߣҩҩǿգЧػƶ߰ЧظЧë߰Cȥë߰ë߰Kûƣǿ߰ԼҪϸĤϵNa,K-ATPøʹϸڸӡҩãǿԼɣļԵӰ죨ҴԣӳЧӦڣٴӦãĹܲȫʧķ˶Ķ٣˥ķ˶ԷӦΣҪΪθϵͳࡣʧüƳЧӢɺȶǿ߰ĹʧdzЧǿ߰ĶͿðƷơаũ߸ŨȣũͰͷӶ
63. Ѫѹҩƽ֬ǿڷѸգиáѪƽļϸCaʹѪͣѪѹ½ļͣŹ״״ΣӹļٴڷĽʹɵڸѪѹӦԭݿˡѪѹĹܲáάסͪῨƽƽѪܽתøƼеǿȵĽѹãΪѪܽתøӶѪܡȩͪڣơڸѪѹΪᡢжԭԻѪѹѡҩصǽѪѹߵѪתҷʺءѪܽϵͳŵɳ̹ɳ̹ɳ̹ѪܽIIҩڸѪѹΪ
1.1
2.1
3.4.ͻǰĤ2塣ѹûȺжȸѪѹٷλԵѪѹҩѪҩÿǿЧ˥֧˽áֶԽѹҩѹǿʹжȸѪѹпƫͷʹԼ۵ƣҲʹҩߵĽ䶾ͣƿֶʺԸѪѹܲߡҩáѪƽĤʹ֮ʧȥȡʹNEDAӶʹڵʵĺϳɺʹ٣ºĽߡͰáоʷ߽áणĩȡŨĩʹĩĤȶӶֹͷŲѹáӦλԵѪѹຣѹҩڸѪѹºͣײҩԡµѪأӦʵءຣһ˹ϳɵܦ1ҩᡢжȸѪѹܲ߸ΪáƣѪŽѹҩΪͷNOѪźѪСۼѹǿѸٶݡ뾲ΣܿڷҪƸѪѹΣҲڳѪ˥ߣļм͡ĪᶨѪƽडມɳມɶມຣͨżŵضͪɫ֣5-ɫǰлغϳɴٽԴ
64. ĽʹҩͣûƣɲNOƽҩãŹ״еƽáҪžʹѪ٣ݻĩѹұͣ͡ٴӦãƺԤĽʹӦͷʹλԵѪѹעƼѪ쵰Ѫ֢ɾעԿѪѹۼѹ߽áضյض˫״ĪпѪСãͪҶضڹIJĽʹƣἰжȸѪѹҲнϺõЧ겡ˡʧЧάסҴ͡Ѫѹ˥иá
65. Ӳҩ
һ Ѫ֬ҩ
1. HMG-CoAԭøƼ工͡øƵ̴ϳٶȣѪLDL-Cˮƽ½õĵѪ֬ãܽTCLDL-C,ʼԡڼԻǼԸߵ̴Ѫ֢͡շ͡͡
2. ֭ϼϩѡΪߵ̴Ѫ֢ڿڷڵ֭ϡڳ뱽ͱסມػƶ߰״ءڷѪҩ֬άҩADEKҶᡢijЩؽϣӰЩҩպЧӦáп沴ϰ
3. ȱأȱǿ֬øLPLĻԡVLDLTG,HDL,ѪСۼٴҪTGΪĸ֬Ѫ֢зŵآءDZȡ
4. ٴࣩͨ;Ӱ֬ĴлҪΪVLDLIJƸ֬Ѫ֢ѪƫͷʹͷʹԶѪ˨˨ڶѣ֢˵ȡаĪ˾ʹ硢ιȫߡ
ҩTCLDL-CTGVLDLӰ졣Ҫͨʡٴڸ֬Ѫ֢II͡رڴͼԸߵ̴Ѫ֢ߡĿǰеʹ併LDL-Cʹɫ˵ҩVEVC,ҪкǿĿԡ
ϩ֬
1. w-6ϩ֬뵨̴ϲתΪ֭ųпѪСѪܵáٴڸ֬Ѫ֢Ӳ
2. w-3ϩ֬ʮ̼ϩƸϳ֬ʺ֬ãܴٽ̴йɷֹӲٴڸ֬Ѫ֢ӲIJ
ġ Ұ̴ֹڶڳ֬ʹɣѪСۼҪڸ֬Ѫ֢TCTGLDLVLDLԸ༲иЧеøøEơ
66. ҩף૱ᡢֶ֧εơءͬתϵͳȻƺˮաѪؼۺ֢ԼжúѪãٴˮףԷˮˮףԤ˥ߣ˥ˣٶųҪڱͱסˮࡢ廯жӦУˮңΣθӦԵȣظܲȫʹ缰СãߵѪ֢иáຣԶСܽˣơתϵͳȻƺˮնµѪءҩáѹúͿáٴӦˮѡҩѪѹ֢ӦңµѪأעⲻҪżҩǿ߰⻯ɵɺãɵʧӦʱءӲ߽ãѪ֢ʹ综áܲȫѪǣ߽ãӦणԶСԶ˺ͼϹܣֱѡͨƵգʹųӶѪá¶֯ˮãѪáٴӦԤ˥ߣˮۡĹܲȫߺ߽áҩɽ洼Դ
67. ƶѪҩҶᡢVB12
68. ѪҩͿѪҩάKѪҩǺϳѪøԭѪӵıʡάKȱ֢ҩѪƵ׳ĵʹаױᡢᡣأѪҩΪӰάɣпסѪСۼѪճȼáڷѪ˨˨ԼɷֹѪ˨γɺѪѪ֢ĸڡ³ѪһӦͣҩ㾫ԿܲȫظѪѹԳѪǼĤIJˡиѪѲߡ˫㶹أҪڷѪ˨Լ׳Ѫͬءơ˨øøҪڼѪ˨˨ԼӴҪӦΪѪøǰлء˫״ĪɿĽʹड̵ҩȻ李N-װᡢ强µȣҩɴȱȣƽҩءƼءɫơͪҡɡƷȡ
69. ϵͳҩ
1. ͨ⡪ءATPø̼ơ̼ơƽM壬θڣͨ⡪ءATPøγɱĤ飨γɱĤĻءùء
2. ҩθøøø
3. ֹҩհͪµ¡
4. кҩþơ̪ࡢҺʯ͡Դ
5. ֹкҩطŵҩ̿߶ʽ̼顣
6. ҩȥᡢȥᡣ鰷ҩ H1ͼп鰷áááٴڱ̬Ӧζ֢Ż¡ʧߡӦΪ˯ȡH2ҩҪ涡涡Ī涡ȡҪ
70. ӹƽ˷ҩأҪǿӹٴʹ߲ԼѪҪ˷ӹѪܡٴڲӹԭӹѪƫͷʹڴ߲ѪӲ״ߡǰء
71. ƤʼأЧɵɡ⻯ɵɡЧɡɵȡЧɡɵȡƤʼأȩͪȥƤͪżأƤʹܼˡ